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MEDICINE AND HEALTH

Christopher F. Rufo Thrown to the Wolves A physician reveals the nightmare of transgender ideology in a major children’s hospital. Christopher Rufo

https://www.city-journal.org/article/transgender-ideology-and-the-corruption-of-medicine

I have been engaged in an ongoing dialogue with a physician who works in a major children’s hospital in a blue city. This physician has witnessed firsthand how transgender ideology has captured the medical profession and jeopardized the first commandment of the healing sciences: do no harm.

He has now chosen to speak out, on condition of anonymity, because he is alarmed by the sudden corruption of the medical community. His colleagues, many of whom oppose transgender interventions, have so far chosen to stay silent. This interview has been edited for length and clarity. 

Christopher Rufo: Please begin by setting the scene. What’s it like in a major children’s hospital in the United States regarding transgender interventions for children?

Physician: I think the best way to answer that question is to talk about the cultural shift that happened in 2020, because transgender ideology and Covid are inextricably linked. Normally, doctors operate by the authority of the professional societies that govern our specific practice. That worked because the individuals in those institutions were reliable, intelligent, and thoughtful. But with Covid in 2020, we started getting medical decrees without peer review or evidence—you saw this with masks, social distancing, and emergency-use authorizations. These decrees were expressed as something that everyone had to do, without justification based on sound science. The other thing was censorship. If you were to ask questions or express doubt about these medical decrees, you would be ostracized within your department, and you stood a good chance of being publicly humiliated, severely reprimanded, or fired.

That’s when transgender ideology really took off. Within these academic institutions, so-called experts in the field of transgender medicine would simply declare that puberty blockers and other interventions were the gold standard of care. The evidence to support this is completely fraudulent, but no dissent was permitted. Everyone within the medical community knew that if he questioned transgender ideology, he would suffer the same type of repercussions that had happened during Covid. The best way to describe the environment would be as an authoritarian, censorious culture that discourages any meaningful debate and encourages the demonization of anyone who asks questions.

Dem Expert Witness Couldn’t Cite Evidence of Benefits of Trans Procedures for Children By Matt Margolis

benefits-of-trans-procedures-for-children-n1703599

On Wednesday, Rep. Dan Crenshaw (R-Texas) grilled a so-called “expert” witness on the issue of transgender procedures for women, during which she failed to cite even a single study showing that cross-sex hormones, puberty blockers, or surgeries have any positive impact.

Dr. Meredithe McNamara, an assistant professor of pediatrics at the Yale School of Medicine, testified in a hearing in opposition to a provision that would block federal funding for hospitals that provide transgender services for minors.

“This is taxpayer money, and when 70% of taxpayers opposed these barbaric treatments on minors, then taxpayers should not fund it,” Crenshaw told her.

During the exchange, McNamara accused Crenshaw of cherrypicking data to support his position against transgender procedures for children.

“It is very unscientific and flawed to pick a single study or a single statistic and to discuss it in isolation,” she said.

“Totally agree,” Crenshaw said.

“All the medical experts are able to talk about all the evidence as a whole,” she added.

“Totally agree. So it’s good to look at systematic reviews right?” Crenshaw asked. “That’s the gold standard of evidence when you’re trying to understand whether something works or whether it doesn’t. So the British Journal of Medicine looked at 61 systematic reviews with the conclusion that, quote, ‘there is great uncertainty about the effects of puberty blockers, cross-sex hormones and surgeries in young people.’ Journal of Endocrine Society came up with the same conclusion. Even the American Academy of Pediatrics — all cite the lack of evidence.”

“So here’s the thing,” Crenshaw continued. “If you’re doing a therapy, and it’s you know, temporary, whatever, fine, maybe let’s try let’s see if it works. But when you’re talking about permanent physiological changes, do you not agree just from an ethical standpoint that you might want extremely strong evidence of the benefits and there is no systematic review, that that states that there is strong evidence of benefits?”

Medical Journal’s False Consensus on ‘Gender-Affirming Care’ Springer has decided to retract a paper, that received activist blowback, on a technicality. By Leor Sapir and Colin Wright

https://www.wsj.com/articles/medical-journals-false-consensus-on-gender-affirming-care-sex-change-procedure-transgender-f10cd52b?mod=opinion_lead_pos7

A federal court on Tuesday temporarily blocked enforcement of a Florida law that prohibits the administration of sex-change procedures on children under 18. The opinion, by Judge Robert L. Hinkle, leans heavily on medical and scientific rationales to argue that it is unconstitutional to ban the use of puberty blockers, cross-sex hormones and surgery on teenagers who feel alienated from their bodies.

Twenty states maintain age restrictions on sex-change procedures, and the problem they face is explaining to judges that American medical associations aren’t following the best available evidence. This is known to European health authorities and has been reported in such prestigious publications as the British Medical Journal. But American judges need some way to evaluate conflicting scientific authorities—especially as institutions responsible for ensuring that medical professionals have access to high-quality research aren’t functioning as they should.

A case in point: Springer, an academic publishing giant, has decided to retract an article that appeared last month in the Archives of Sexual Behavior. The retraction is expected to take effect June 12.

The article’s authors are listed as Michael Bailey and Suzanna Diaz. Mr. Bailey is a well-respected scientist, with dozens of publications to his name. The other author writes under a pseudonym to protect the privacy of her daughter, who suffers from gender dysphoria.

Their new paper is based on survey responses from more than 1,600 parents who reported that their children, who were previously comfortable in their bodies, suddenly declared a transgender identity after extensive exposure to social media and peer influence. Mr. Bailey’s and Ms. Diaz’s sin was to analyze rapid onset gender dysphoria, or ROGD. Gender activists hate any suggestion that transgender identities are anything but innate and immutable. Even mentioning the possibility that trans identity is socially influenced or a phase threatens their claims that children can know early in life they have a permanent transgender identity and therefore that they should have broad access to permanent body-modifying and sterilizing procedures.

The Truth About ‘Puberty Blockers’ The FDA hasn’t approved them for gender dysphoria, and their effects are serious and permanent. By Gerald Posner

https://www.wsj.com/articles/the-truth-about-puberty-blockers-overdiagnosis-gender-dysphoria-children-933cd8fb?mod=opinion_lead_pos6

The fashion for transgenderism has brought with it a new euphemism: “gender-affirming care,” which means surgical and pharmacological interventions designed to make the body look and feel more like that of the opposite sex. Gender-affirming care for children involves the use of “puberty blockers”: one of five powerful synthetic drugs that block the natural production of sex hormones.

The Food and Drug Administration has approved those medications to treat prostate cancer, endometriosis, certain types of infertility and a rare childhood disease caused by a genetic mutation. But it has never approved them for gender dysphoria, the clinical term for the belief that one’s body is the wrong sex.

Thus the drugs, led by AbbVie’s Lupron, are prescribed to minors “off label.” (They are also used off-label for chemical castration of repeat sex offenders.) Off-label dispensing is legal; some half of all prescriptions in the U.S. are for off-label uses. But off-label use circumvents the FDA’s authority to examine drug safety and efficacy, especially when the patients are children. Some U.S. states have eliminated the need for parental consent for teens as young as 15 to start puberty blockers.

Proponents of puberty blockers contend there is little downside. The Department of Health and Human Services claims puberty blockers are “reversible.” It omits the evidence that “by impeding the usual process of sexual orientation and gender identity development,” these drugs “effectively ‘lock in’ children and young people to a treatment pathway,” according to a report by Britain’s National Health Service, which cites studies finding that 96% to 98% of minors prescribed puberty blockers proceed to cross-sex hormones.

COVID The Curious Tale of Hydroxychloroquine Robert Clancy

https://quadrant.org.au/opinion/covid/2023/05/the-curious-tale-of-hydroxychloroquine/

The discipline of medicine has changed. Its traditional cohesion and leadership have fractured into multiple disconnected specialty groups, allowing powerful commercial and political forces to increase control over both structure and function of medical practice. The COVID era burst through boundaries long taken for granted.

A major driver of opinion about COVID has been the World Health Organisation (WHO). Its Health Emergencies Programme in its proposed form, designed to strengthen disease-specific systems and capacities, including for vaccines, pharmaceuticals and other public health interventions, may be a serious threat to independent local health systems. Given it is an unelected body responsive to powerful lobbies, and a with a performance short of wide approval in its overarching role in the recent pandemic, there is reason to tread carefully.

I have practised as a physician in Australia for half a century. I recall when we knew (and revered) the name of the President of the Royal Australasian College of Physicians, while living in fear of their Chief Examiner as we sought qualification! They were great men and women and were the exemplars for ethical practice. Today they only occasionally question imperfect narratives or challenge the ethics of prevailing medical practice, risking being part of the problem rather than a solution.

Recently I was invited to speak at a symposium “Medicine at the Crossroads in the COVID Era”. I sought a topic that illustrates contemporary challenges to Western medicine. Few topics could be more relevant than threats to the doctor-patient relationship, and to science-based medicine seen in the COVID-19 pandemic. So I chose “The curious tale of hydroxychloroquine (HCQ)” as a metaphor for the distortion COVID imposed on clinical practise, driven by misinformation aimed at supporting a flawed narrative originating from the highest sources of medical influence.

I am a clinical immunologist. I have a special interest in chronic inflammatory disease and the immunology of the airway. Among the valuable drugs in my clinical practice was HCQ, for which I wrote approximately 20,000 prescriptions without any observed major side effect.  It proved to be a safe and effective medication that blocked antigen-promoting pathogenic immune responses in patients with autoimmune or hypersensitivity diseases.

COVID made HCQ a household name. No medication attracted more brutal and remorseless assault. It was subjected to derision and negativity by medical professionals and the public alike. HCQ presents the dilemma that embodies the extremes of the narrative and science of COVID. In this context and over the last three years, popular narrative and science have gone down quite different paths.

Doctors Having To Ration Cancer Drugs Amid Shortages

https://kffhealthnews.org/morning-breakout/doctors-having-to-ration-cancer-drugs-amid-shortages/

ABC News reports on impacts ongoing drug supply shortages are having on cancer treatments, with some doctors having to decide which of their patients to treat. Also, Pfizer said an experimental combination of antibiotics is effective at treating some drug-resistant bacterial infections.

ABC News: Cancer Drug Shortage Is Forcing Doctors To Decide Which Patients Get Treatment  Just six weeks ago, Greg DeStefano began a new chemotherapy combination. The 50-year-old, from Northbrook, Illinois, had recently been diagnosed with his fourth round of cancer and doctors were hopeful the medication would treat the tumors growing in his neck. DeStefano was responding well, but then, in late May, he got a call from his doctor and was told one of the three drugs he was receiving — carboplatin — was under a global shortage and because of the way the hospital had to prioritize treatments, he wouldn’t be qualified to receive it anymore. (Kekatos, 6/2)

Trump Needs a Reality Check on the mRNA Jabs By Stacey Lennox

https://pjmedia.com/news-and-politics/stacey-lennox/2023/06/02/trump-needs-a-reality-check-on-the-mrna-jabs-n1700155

President Donald Trump returned to Iowa on Thursday after canceling a rally due to weather in the first-in-the-nation caucus state earlier in May. He met with smaller groups of Iowa voters in a few events canvassing the state. A voter told him at one stop, “We have lost people because you supported the jab.” Then she appears to ask him what he would do differently. Given all we know about the clot shots now, Trump’s response was astonishing.

“Well, you know, everyone wanted a vaccine at that time. And I was able to do something that nobody else could have done, getting it done very, very rapidly,” Trump responded. “But I never was for mandates, so I thought the mandates were terrible. And you know, there’s a big portion of the country that thinks it was a great thing.”

Oh, where to begin? First, the portion of the country that thinks the jabs were a great thing will never vote for President Trump. They are on the side of the aisle with Trump’s new best buddy Andrew Cuomo and still wear masks outdoors. A Rasmussen poll noted in January that almost half of Americans believed the shots were causing unexplained deaths, and more than one in four believed they knew some that had died due to the jab.

At the time, 60% of Republicans believed there was a reason to be concerned about the safety of the mRNA shots. Additional studies have been reported since then that implicate the mRNA shots, specifically the spike protein they generate, to a whole host of medical problems from acute onset blindness to impairing the immune system’s ability to fight COVID-19 infections in the future after repeated vaccinations. Evidence about the shot’s role in causing myocarditis in young men continues to accumulate. And honest providers will tell you that they don’t know the long-term prognosis for young Americans who suffered from heart-related adverse events.

Mask Mandates Unmasked Congress must end white coat supremacy and make a case for pandemic reparations. By Lloyd Billingsley

https://amgreatness.com/2023/05/23/mask-mandates-unmasked/

In the early days of the COVID-19 pandemic, Dr. Anthony Fauci said, “There’s no reason for you to be walking around with a mask.” But the longtime director of the National Institute of Allergy and Infectious Diseases (NIAID) soon changed his stance. Although not 100 percent effective, Fauci said, wearing masks is “a symbol for people to see that that’s the kind of thing you should be doing.”

Masks should be worn, he said, even by those who were vaccinated, although they did not need to wear a mask outside. On another occasion, Fauci recommended people wear two face masks. The NIAID boss gave little if any indication that face masks could cause health problems.

“Circumstantial evidence exists that extended mask use may be related to current observations of stillbirths and to reduced verbal motor and overall cognitive performance in children born during the pandemic.” That is the contention of “Possible toxicity of chronic carbon dioxide exposure associated with face mask use, particularly in pregnant women, children and adolescents,” a recent study out of Germany. The paper highlights “the toxicological aspects of wearing a mask for special user groups resulting from a low-level CO2 exposure.”

During the COVID pandemic in 2020, 77 percent of nations introduced mask requirements, and 58 percent of people around the world “have been confronted with a mask obligation.” In many countries, “children in schools in particular are/have been heavily exposed to the mandatory wearing of masks for long periods.” As it happens, that is not good for the children.

“Fresh air has around 0.04% CO2, while wearing masks more than five minutes bears a possible chronic exposure to carbon dioxide of 1.41% to 3.2% of the inhaled air,” the authors observe. “U.S. Navy toxicity experts set the exposure limits for submarines carrying a female crew to 0.8% CO2 based on animal studies which indicated an increased risk for stillbirths.” 

In addition, “data exists on the exposure of chronic 0.3% CO2 in adolescent mammals causing neuron destruction, which includes less activity, increased anxiety and impaired learning and memory. There is also data indicating testicular toxicity in adolescents at CO2 inhalation concentrations above 0.5%.”

Why Cancer Drugs Are Being Rationed The government squeeze on generic profits is leading to shortages.

https://www.wsj.com/articles/drug-shortages-price-controls-government-fda-white-house-cancer-treatments-b2d08ba4

Politicians like to grouse about high drug prices. Well, now we’re seeing what happens when drug prices are too low: Shortages of essential medicines, which are a portent of what’s to come with the Inflation Reduction Act’s price controls.

Drug shortages aren’t new, but the number in short supply has grown as generic prices have fallen. The American Society of Health-System Pharmacists lists 301 drugs in short supply, up from 202 five years ago. These include many local anesthetics, basic hospital drugs, chemotherapy drugs and liquid albuterol for lung ailments.

The American Cancer Society warned this month that “first-line treatments for a number of cancers, including triple-negative breast cancer, ovarian cancer and leukemia often experienced by pediatric cancer patients,” are facing shortages that “could lead to delays in treatment that could result in worse outcomes.” Healthcare providers say they’re having to limit access to some drugs to the sickest patients. They can substitute therapeutic alternatives when possible, but this increases risk of medication errors and inferior results. What’s going on?

Headlines have focused on shortages of the ADHD drug Adderall and new weight-loss treatments, which owe to increased demand. But most drugs in short supply are older generics that are off-patent and complicated to make. Manufacturers have stopped producing them because profit margins are too thin, resulting in one or two suppliers.

Jeffrey H. Anderson: The Harm Caused by Masks A new study suggests that the excess carbon dioxide breathed in by mask-wearers can have major health consequences.

https://www.city-journal.org/article/the-harm-caused-by-masks

Evidence continues to mount that mask mandates were perhaps the worst public-health intervention in modern American history. While concluding that wearing masks “probably makes little or no difference” in preventing the spread of viruses, a recent Cochrane review also emphasized that “more attention should be paid to describing and quantifying the harms” that may come from wearing masks. A new study from Germany does just that, and it suggests that the excess carbon dioxide breathed in by mask-wearers may have substantial ill-effects on their health—and, in the case of pregnant women, their unborn children’s.

Mask-wearers breathe in greater amounts of air that should have been expelled from their bodies and released out into the open. “[A] significant rise in carbon dioxide occurring while wearing a mask is scientifically proven in many studies,” write the German authors. “Fresh air has around 0.04% CO2,” they observe, while chronic exposure at CO2 levels of 0.3 percent is “toxic.” How much CO2 do mask-wearers breathe in? The authors write that “masks bear a possible chronic exposure to low level carbon dioxide of 1.41–3.2% CO2 of the inhaled air in reliable human experiments.”

In other words, while eight times the normal level of carbon dioxide is toxic, research suggests that mask-wearers (specifically those who wear masks for more than 5 minutes at a time) are breathing in 35 to 80 times normal levels.

The German study, a scoping review of existing research, aimed “to investigate the toxicological effects of face masks in terms of CO2 rebreathing on developing life, specifically for pregnant women, children, and adolescents.” The latter two groups, of course, have been among those most frequently subjected to mask mandates in schools, despite Covid’s low levels of risk for them and the evidence that masks don’t work.